In Vitro Automatic Simulated Digestion System (SDS III)
UniVOOK Industry-Global Exclusive Distributor and Afer-sales Servicer
Precise Livestock Farming: Offer What Animals Exactly Need !
In modern livestock production, precise feeding and enhance ingredients’ utilization rate have always been key solutions for achieving sustainable development of the feed industry and livestock breeding. Clearly, the prerequisite is that we must accurately and real-timely obtain the effective digestible energy value of these feeds and feed ingredients, discover more suitable feed enzymes……
In Vitro Automatic Simulated Digestion System for Monogastric Animals (SDS III) is helping feeds and animal nutrition companies, livestock farming organizations achieve these goals worldwide: High Efficiency, Standardization, Precise, Data-driven, Animal Welfare Consideration……
The Industrialized Techniques To Evaluate Feeds And Feedstuffs
Simulated Digestion System (SDS III) is a patented bionic in vitro platform designed to mimic gastrointestinal digestion in monogastric animals. It provides standardized, integrated, automated solutions for evaluating nutrient bioavailability (e.g., available energy, amino acids) in feed and feedstuffs, as well as assessing feed enzyme bio-efficacy.
SDS III establishes a new benchmark for modern feed evaluation by combining the physiological relevance of in vivo digestion with the efficiency and standardization of advanced in vitro technology. SDS III represents a significant technological advance in biomimetic feed evaluation: innovative and patented automatic digestion device with species-specific simulated digestive kits for poultry, swine and pet animals, closely reproduce physiological digestive processes. Through the fully automated synchronization of enzyme delivery, pH adjustment, buffer infusion, and hydrolysate removal, SDS III transforms conventional manual in vitro assays into a highly standardized, fully automated workflow. By enabling rapid, reliable, and sustainable nutritional assessment, SDS III addresses longstanding challenges in feed research and quality control and supports the global transition toward ethical animal research in accordance with the 3Rs principles (Replacement, Reduction, and Refinement).
• Precisely reproduces dynamic digestive conditions (pH, temperature, enzyme activity, transit time).
• Offers high flexibility and ease for analyzing the bioavailability of major nutrients via species- and nutrient-specific simulated digestive fluid kits
• Validated test outcomes, achieves reputation in feed and animal nutrition industry worldwide;
• Generates results 66 times faster than conventional in vivo trials, supporting high-throughput screening of feed ingredients.
• Cuts analytical costs by approximately 90% compared with live animal experiments.
• Minimizes manual operation and reliance on technicians, ensuring consistent, reproducible results across operators and laboratories.
• Reduces inter-laboratory variability with standardized protocols and calibrated instrumentation.
• Provides a fully animal-free feed evaluation method consistent with the 3Rs principle (Replacement, Reduction, Refinement) in animal research.
How Does In Vitro Automatic Simulated Digestion System Support You?
1)- Build unique and dynamic feedstuffs nutrition by precisely evaluating the true energy values of feeds and feed ingredients;
2)- Quality monitoring for feeds and feed raw materials;
3)- Identify non-conventional or non-grain feed raw materials;
4)- Feeds formula optimization;
5)- Precisely livestock breeding;
6)- Feed enzymes’ performance evaluation;
7)- Multienzymes premix designing and evaluation;
8)- Phytase and available phosphorus determination;
9)- Build feeding standards, dynamic nutritional requirements.

Core Technologies and Advantages of SDS (III)
1- Automatic Control
2- Dual-modules Compatibility: Vertical and Horizontal

Horizontal Digestion Module
- Automatically executes the digestion steps of stomach, small intestine and large intestine; Automatically adds simulated digestive fluid and automatically cleans the digested by products.
- Overcomes the residual problem of feed, eliminating the need for sample migration.
- Highly simulates the digestive condition of in vivo;
- High simulation precision: repeated tests CV < 1.5%;
- Measure the biological utilization of nutrients by simulating the digestion and absorption process of nutrients in the gastro-intestine tract of animals
Vertical Digestion Module
- With an independent motor, the mixing speed is adjustable; Automatically executes the digestion steps of stomach, small intestine and large intestine; Automatically adds simulated digestive fluid
- Double glass structure reaction tube, circulating water constant temperature, comparable digestive condition to those of in vivo;
- High simulation precision: repeated tests CV < 1.5%;
- Suitable for in vitro digestion evaluation of feed enzymes;

SDS System Serves Feeds and Animal Nutrition Industries Worldwide
Simulated digestion system (SDS III) is jointly developed by Institute of Animal Science, Chinese Academy of Agricultural Sciences (IAS, CAAS) and Hunan Zhongben Intelligent Technology. UniVOOK Industry is authorized as the global exclusive distributor and after-sales service provider, take fully responsibility of markets promotion and sales business for SDS III system and related reagents worldwide.
300+
Feeds and Animal Enterprises
250+
Serves Millions Tons of Feeds
Worldwide
Serves Feeds&Animal Nutrition Worldwide

Not Only SDS III, We Are Ready To Support You More –
From digestion to metabolism and animal growth sensing, IAS-CAAS has established a complete-chain “Feeds Nutritional Evaluation and Utilization” technology platforms and systems, including In Vitro Automatic Simulated Digestion System (SDS III), Automatic Respiration Calorimetry System (CRS-1), Poultry Growth Intelligent Sensing System (PGIS), constructed a globally unified animal nutrition service platform:
- Standardized and globally unified methods for determining the effective energy values of feed and feed raw materials;
- Standardized and globally unified methods for determining the digestibility of amino acids/proteins;
- Standardized and globally unified methods for determining the effective phosphorus content;
- Feed enzymes based on the three major technical platforms of SDS/CRS/PGIS;
- One-stop feed and animal nutrition technology service platform based on the three major technical platforms of SDS/CRS/PGIS.
As the global exclusive distributor and after-sales service, UniVOOK Industry is supporting feed and animal nutrition companies and organizations worldwide for achieving their goals of precise livestock farming and sustainable development by SDS III.