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5-Hydroxymethylfurfurale (5-HMF)

Formula C6H6O3
Molecular weight 126.11
CAS No. 67-47-0
EC No. 200-654-9
Synonyms 2-Furaldehyde, 5-(hydroxymethyl)-; 2-Furancarboxaldehyde-5-(hydroxymethyl)-; 2-Hydroxymethyl-5-furfural; 5-(Hydroxymethyl)furfural; 5-Hydroxymethyl-2-formylfuran; 5-(Hydroxymethyl)-2-furaldehyde; 5-(Hydroxymethyl)-2-furancarbonal; 5-(Hydroxymethyl)-2-furancarboxaldehyde; 5-(Hydroxymethyl)-2-furfural; 5-Hydroxymethylfuraldehyde; 5-(hydroxymethyl)furan-2-carbaldehyde; 5-Oxymethylfurfurole; Hydroxymethylfurfural; Hydroxymethylfurfuralaldehyde;


5-Hydroxymethylfurfurale, also known as 5-HMF or Hydroxymethylfurfurale , is indeed derived from sugars and is considered a key link between biomass and furan-based chemicals. This compound is a crucial intermediate in the conversion of biomass into valuable and sustainable organic chemicals.


Hydroxymethylfurfurale is a key player in the synthesis of renewable and sustainable organic chemicals. In the food and beverage sector, 5-HMF acts as a precursor for natural sweeteners, contributing to the development of healthier alternatives. Its reactive functional groups make it an ideal candidate for polymerization reactions, fostering the creation of biobased polymers with enhanced properties in the materials industry. Furthermore, 5-HMF’s potential as a platform chemical enables its utilization in pharmaceuticals, biofuels, and diverse high-value compounds.


Features: 5-Hydroxymethylfurfurale (5-HMF)

Derivation from Sugars:

5-Hydroxymethylfurfurale is often produced from sugars through various chemical processes, including dehydration reactions of hexoses (six-carbon sugars like glucose and fructose). This allows it to be sourced from renewable biomass, such as plant materials, making it an attractive option for sustainable chemistry.

Versatility in Synthesis:

The functional groups and reaction sites present in 5-Hydroxymethylfurfurale make it highly versatile. Its structure allows for different chemical transformations, enabling its use as an intermediate in the synthesis of various valuable chemicals and materials.

Biorenewable Source:

Derived from renewable biomass, Hydroxymethylfurfurale aligns with eco-friendly and sustainable practices, making it an ideal choice for manufacturers committed to reducing their environmental footprint.

Sweetener Precursor:

Recognized as a key precursor in the production of furan-based sweeteners, Hydroxymethylfurfurale plays a crucial role in the development of natural and healthier alternatives in the food and beverage industry.

Antioxidant Potential:

With inherent antioxidant properties, 5-HMF finds applications in the formulation of antioxidants for food preservation and cosmetics, protecting against oxidative degradation.


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5-Hydroxymethylfurfurale (5-HMF) is derived from sugars and is the link between biomass and furan-based chemicals. Due to its functional groups and reaction sites, 5-hydroxymethylfurfural is a versatile, renewable organic intermediate.

Intermediates: 5-Hydroxymethylfurfurale (5-HMF) is used as intermediates in the Synthesis processes of following products::
mark 2,5-Furandicarboxylic acid: replacement for terephthalic acid;
mark 2,5-Dimethylfuran:
mark 2,5-bis(hydroxymethyl)furan;
mark 2,5-Furandimethanol;
mark 5-Methyl furfural;
mark 2,5-Hexanedione;
mark (5-Methylfuran-2-yl)methanol;
mark Dimethyl furan-2,5-dicarboxylate;
mark Bio-based 5-Hydroxymethylfurfurale is considered as a substitute for formaldehyde in phenolic resin;
mark Furan resin: Used to make furan resin, which has good heat resistance and electrical insulation.
mark Pharmaceutical field: 5-HMF and its derivatives such as 2,5-furandioic acid have potential application value in medicine. They can be used as active ingredients in drugs to treat inflammation, antioxidants, allergic reactions, protect nerve cells, and improve memory. In addition, 5-HMF itself is also a compound with pharmaceutical activity and is present in a variety of traditional Chinese medicines
mark Food additive: In the food industry, 5-HMF can be used as a flavoring, especially in the production of fried foods and spicy foods.
mark Substitutes for petroleum products: 5-HMF and its derivatives can serve as substitutes for petroleum fuels, especially in the conversion of polysaccharides into liquid alkanes in two-phase systems.
mark Polymer materials: 5-HMF, as a monomer, can be used to synthesize optically active, biodegradable polymer materials, which can be used in synthetic fibers, rubber and casting industries.
Shelf Life

Under ambient temperature, the shelf life is 12 months

Health & Safety

For more details and safety recommendations regarding the use of the product, please consult our Material Safety Data Sheet (MSDS), or Contact With our Product Manager.


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